Andrew Luck, the No. 1 overall draft pick who has gotten most of the credit for Indy's remarkable turnaround, was 20 of 37 for 240 yards with one touchdown and one interception and became only the second Colts' rookie to throw top 3,000 yards in a season. The other: Peyton Manning.
And Pagano was there to see — and savor — every precious moment of it again.
Two weeks ago, Pagano returned to Lucas Oil Stadium for the first time since being diagnosed with leukemia Sept. 26, and just having him around on game-day is certainly making an impact.
"I talked to Coach Pagano before the game and he just told me to 'stretch and cut, stretch and cut,'" Hilton said, describing the advice Pagano gave him about returning kicks. "So I was able to stretch and my blockers did a good job of getting in front of their dudes, made two guys miss me and I went to the house."
This time, it wasn't just the players who got to see Pagano.
During a fourth-quarter break, team owner Jim Irsay and Pagano walked out of the owner's box together and waved to crowd, which gave them a standing ovation. Two Colts cheerleaders also shaved their heads in support of Pagano, who has lost his hair as he continues to undergo chemotherapy treatments, between the third and fourth quarters as part of a promise for a fundraising effort for leukemia research
The Bills (4-7) couldn't compete with all of that.
C.J. Spiller ran 14 times for 107 yards, his sixth straight game with 100 yards from scrimmage. Ryan Fitzpatrick was 17 of 33 for 180 yards with one TD and one interception, and Stevie Johnson caught six passes for 106 yards, his first 100-yard game since December 2011.
Though the Bills did end their red-zone touchdown drought with Fitzpatrick's 1-yard TD pass to Lee Smith with 11:30 left in the game, it just wasn't enough against Hilton and the Colts.